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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBA1 All Species: 25.45
Human Site: S21 Identified Species: 56
UniProt: P22314 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22314 NP_003325.2 1058 117849 S21 G P D P K P G S N C S P A Q S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092142 1058 117902 S21 G P D P K P G S N C S P A Q S
Dog Lupus familis XP_538014 1015 112483 S21 G P D P K P G S N C S P A H S
Cat Felis silvestris
Mouse Mus musculus Q02053 1058 117790 S21 G P D P K P G S N C S P A Q S
Rat Rattus norvegicus Q5U300 1058 117769 S21 G P D P K P G S N C S S A Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080185 1059 117949 S21 G S E T K T G S N C S S S K S
Zebra Danio Brachydanio rerio NP_998227 1058 118200 S21 G S E T K T G S H C S S S N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477310 1191 130740 N166 N N N V S S S N N N S N N S T
Honey Bee Apis mellifera XP_394434 1049 117087 A21 P A K K R R V A A T T G G A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795302 1054 117556 S23 K R R L E Q E S N N T N Q N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22515 1024 114248 G27 S R Q L Y V L G K E A M L K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 90.2 N.A. 95.5 96.4 N.A. N.A. N.A. 77.6 78.8 N.A. 54.1 62.2 N.A. 65.2
Protein Similarity: 100 N.A. 99 92.1 N.A. 97.5 98.1 N.A. N.A. N.A. 90.1 90 N.A. 67.3 76.9 N.A. 80.7
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 93.3 N.A. N.A. N.A. 53.3 46.6 N.A. 13.3 0 N.A. 20
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 93.3 N.A. N.A. N.A. 73.3 66.6 N.A. 33.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 10 0 10 0 46 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 % C
% Asp: 0 0 46 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 19 0 10 0 10 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 64 0 0 0 0 0 64 10 0 0 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 10 64 0 0 0 10 0 0 0 0 19 0 % K
% Leu: 0 0 0 19 0 0 10 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % M
% Asn: 10 10 10 0 0 0 0 10 73 19 0 19 10 19 0 % N
% Pro: 10 46 0 46 0 46 0 0 0 0 0 37 0 0 0 % P
% Gln: 0 0 10 0 0 10 0 0 0 0 0 0 10 37 0 % Q
% Arg: 0 19 10 0 10 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 19 0 0 10 10 10 73 0 0 73 28 19 10 73 % S
% Thr: 0 0 0 19 0 19 0 0 0 10 19 0 0 0 10 % T
% Val: 0 0 0 10 0 10 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _